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| Torres-Silva,Carolina Furtado; Repolês,Bruno Marçal; Ornelas,Hugo Oliveira; Macedo,Andréa Mara; Franco,Glória Regina; Junho Pena,Sérgio Danilo; Tahara,Erich Birelli; Machado,Carlos Renato. |
| Abstract Trypanosoma cruzi is the etiological agent of Chagas disease, a public health challenge due to its morbidity and mortality rates, which affects around 6-7 million people worldwide. Symptoms, response to chemotherapy, and the course of Chagas disease are greatly influenced by T. cruzi‘s intra-specific variability. Thus, DNA mutations in this parasite possibly play a key role in the wide range of clinical manifestations and in drug sensitivity. Indeed, the environmental conditions of oxidative stress faced by T. cruzi during its life cycle can generate genetic mutations. However, the lack of an established experimental design to assess mutation rates in T. cruzi precludes the study of conditions and mechanisms that potentially produce genomic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: T. cruzi; DNA; Mutation frequency; H2O2. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000300466 |
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| Agarwal,Sheela; Shaheen,Robina. |
| The purpose of the present work was to evaluate both the antioxidant response system and oxidative stress in leaves from bitter gourd (Momordica charantia L) subjected to NaCl, UV-B and water stresses at three different stages of plant growth: pre-flowering, flowering and post-flowering. Except for peroxidase (POX), all enzyme activities including superoxide dismutase (SOD), catalase (CAT), polyphenol oxidase (PPO), glutathione reductase (GR), as well as concentrations of ascorbate (ASA), hydrogen peroxide (H2O2) and thiobarbituric acid reactive substances (TBARS) exhibited maximum values at the flowering stage under all three stresses. All the enzyme activities, SOD, CAT, POX, PPO, GR and the concentrations of ASA, H2O2 and TBARS were elevated under NaCl... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidative enzymes; Environmental stresses; H2O2; Ion concentration; Thiobarbituric acid-reactive substances. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202007000200007 |
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